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Several challenges facing HIV research
There are several reasons why finding a cure for HIV/AIDS has been such a long road of challenge after challenge. HIV is such a complex, multifaceted, ever-changing virus that it makes it difficult to keep up with.
Some of the current general challenges facing HIV research include:
•Reaching populations most at risk of HIV infection and transmission
•Ensuring that research takes place with participants' fully-informed consent, meaning that they fully understand both the risks and benefits of the trial
•Developing safe and effective HIV vaccine candidates to test via clinical trials with both human- and nonhuman primates
•Gaining a better understanding of immune response mechanisms in humans
•Taking HIV comorbidities into account in research, so any potential cure would benefit as many people as possible
•Increasing focus on the study of remission observed in rare patients who have stopped their treatment
•Defining exactly what is meant by a "cure" for HIV
•Decreasing the stigma that still surrounds HIV, with the aim of minimizing its impact on participation in HIV research
•Gaining a better understanding of how to effectively treat HIV coinfections and manage treatment failures